Fentanyl Withdrawal

First introduced in 1959, and circulated into medicinal use in 1960, fentanyl was originally manufactured as a pain relief medication, or intravenous anesthetic. As a synthetic opioid, fentanyl was found to be highly potent, nearly 50 to 100 times stronger than morphine. It was soon found that–like heroin–fentanyl could produce not only pain relief in patients, but strong feelings of well-being and euphoria. Soon individuals were using the medication illicitly, and the drug entered into Scheduled II classification. By the 1990s, the U.S. was experiencing its first wave of opioid-related overdoses and deaths. 

Fentanyl Withdrawal Symptoms 

Fentanyl is a dangerous drug to use, even in medical settings, because of its high abuse potential. The drug and medication has many side effects that need to be watched out for during normal use, severe side effects in illicit use, and can onset withdrawal symptoms in both medical and non-medical uses. Opioids change the chemical makeup of the brain, and thus how the brain reacts to different substances. So, when fentanyl is removed from the brain suddenly, adverse effects can arise. Fentanyl withdrawal symptoms, which are very similar to other opioid withdrawal symptoms, can include:

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  • Muscle aches.
  • Agitation.
  • Anxiety.
  • Increased tearing. 
  • Runny nose. 
  • Fever.
  • Chills.
  • Insomnia. 
  • Sweating.
  • Yawning.
  • Abdominal cramping. 
  • Changes in pupil size. 
  • Goosebumps. 
  • Cold flashes. 
  • Diarrhea. 
  • Vomiting. 
  • Nausea. 
  • Mood swings.